Leoni Cristina, PhD

Publications

• The mRNA methyltransferase Mettl3 modulates cytokine mRNA stability and limits functional responses in mast cells
  Leoni, C. Bataclan, M. Ito-Kureha, T. Heissmeyer, V. Monticelli, S.
  in Nat Commun (2023) Vol.14 pp3862
  
• Subcapsular sinus macrophages promote melanoma metastasis to the sentinel lymph nodes via an IL-1alpha-STAT3 axis
  Virgilio, T. Bordini, J. Cascione, L. Sartori, G. Latino, I. Molina Romero, D. Leoni, C. Akhmedov, M. Rinaldi, A. Arribas, A. J. Morone, D. Seyed Jafari, S. M. Bersudsky, M. Ottolenghi, A. Kwee, I. Chiaravalli, A. M. Sessa, F. Hunger, R. E. Bruno, A. Mortara, L. Voronov, E. Monticelli, S. Apte, R. N. Bertoni, F. Gonzalez, S. F.
  in Cancer Immunol Res (2022) Vol.10 pp1525-1541
  
• The function of Wtap in N(6)-adenosine methylation of mRNAs controls T cell receptor signaling and survival of T cells
  Ito-Kureha, T. Leoni, C. Borland, K. Cantini, G. Bataclan, M. Metzger, R. N. Ammann, G. Krug, A. B. Marsico, A. Kaiser, S. Canzar, S. Feske, S. Monticelli, S. Konig, J. Heissmeyer, V.
  in Nat Immunol (2022) Vol. pp
  
• RNA-binding proteins and RNA methylation in myeloid cells
  Bataclan, M. Leoni, C. Monticelli, S.
  in Immunol Rev (2021) Vol. pp
  
• An optimized workflow for CRISPR-Cas9 deletion of surface and intracellular factors in primary human T lymphocytes
  Leoni, C. Bianchi, N. Vincenzetti, L. Monticelli, S.
  in PLoS One (2021) Vol.16 ppe0247232
  
• A molecular network regulating the proinflammatory phenotype of human memory T lymphocytes
  Emming, S. Bianchi, N. Polletti, S. Leoni, C. Montagner, S. Chirichella, M. Delaleu, N. Natoli, G. Monticelli, S.
  in Nat Immunol (2020) Vol.21 pp388-399
  
• The contribution of active and passive mechanisms of 5mC and 5hmC removal in human T lymphocytes is differentiation- and activation-dependent
  Vincenzetti, L. Leoni, C. Chirichella, M. Monticelli, S.
  in Eur J Immunol (2019) Vol.49 pp611-625
  
• Epigenetic and transcriptional control of mast cell responses
  Monticelli, S. Leoni, C.
  in F1000Res (2017) Vol.6 pp2064
  
• Dnmt3a restrains mast cell inflammatory responses
  Leoni, C. Montagner, S. Rinaldi, A. Polletti, S. Balestrieri, C. Monticelli, S.
  in Proc Natl Acad Sci U S A (2017) Vol.114 ppE1490-E1499
  Commented in Science (PMID: 28232567 )
• TET2 Regulates Mast Cell Differentiation and Proliferation through Catalytic and Non-catalytic Activities
  Montagner, S. Leoni, C. Emming, S. Balestrieri, C. Barozzi, I. Piccolo, V. Togher, S. Ko, M. Rao, A. Natoli, G. Monticelli, S.
  in Cell Rep (2016) Vol.15 pp1566-79
  
• Epigenetics of T lymphocytes in health and disease
  Leoni, C. Vincenzetti, L. Emming, S.
  in Swiss Med Wkly (2015) Vol.145 ppw14191
  Full Text
• ERK phosphorylation and miR-181a expression modulate activation of human memory TH17 cells
  Mele, F. Basso, C. Leoni, C. Becattini, S. Latorre, D. Lanzavecchia, A. Sallusto, F. Monticelli, S.
  in Nat Commun (2015) Vol.6 pp6431
  Federica Sallusto and Silvia Monticelli equally contributed to this work and are co-corresponding authors.
• Reduced DNA methylation and hydroxymethylation in patients with systemic mastocytosis
  Leoni, C. Montagner, S. Deho, L. De Matteis, G. Marzano, A. V. Merante, S. Orlandi, E. M. Zanotti, R. Monticelli, S.
  in Eur J Haematol (2015) Vol.95 pp566-75
  
• Two functionally distinct subsets of mast cells discriminated By IL-2-independent CD25 activities
  Deho, L. Leoni, C. Brodie, T. M. De Simone, M. Polletti, S. Barozzi, I. Natoli, G. Monticelli, S.
  in J Immunol (2014) Vol.193 pp2196-206