Cecchinato Valentina, PhD

Publications

• The chemokine landscape: one system multiple shades
  Cecchinato, V. Martini, V. Pirani, E. Ghovehoud, E. Uguccioni, M.
  in Front Immunol (2023) Vol.14 pp1176619
  
• Autoantibodies against chemokines post-SARS-CoV-2 infection correlate with disease course
  Muri, J. Cecchinato, V. Cavalli, A. Shanbhag, A. A. Matkovic, M. Biggiogero, M. Maida, P. A. Moritz, J. Toscano, C. Ghovehoud, E. Furlan, R. Barbic, F. Voza, A. De Nadai, G. Cervia, C. Zurbuchen, Y. Taeschler, P. Murray, L. A. Danelon-Sargenti, G. Moro, S. Gong, T. Piffaretti, P. Bianchini, F. Crivelli, V. Podesvova, L. Pedotti, M. Jarrossay, D. Sgrignani, J. Thelen, S. Uhr, M. Bernasconi, E. Rauch, A. Manzo, A. Ciurea, A. Rocchi, M. B. L. Varani, L. Moser, B. Bottazzi, B. Thelen, M. Fallon, B. A. Boyman, O. Mantovani, A. Garzoni, C. Franzetti-Pellanda, A. Uguccioni, M. Robbiani, D. F.
  in Nat Immunol (2023) Vol.24 pp604-611.
  
• Systematic Development of Peptide Inhibitors Targeting the CXCL12/HMGB1 Interaction
  Sgrignani, J. Cecchinato, V. Fassi, E. M. A. D'Agostino, G. Garofalo, M. Danelon, G. Pedotti, M. Simonelli, L. Varani, L. Grazioso, G. Uguccioni, M. Cavalli, A.
  in J Med Chem (2021) Vol.64 pp13439-13450.
  
• β-Arrestin1 and β-Arrestin2 Are Required to Support the Activity of the CXCL12/HMGB1 Heterocomplex on CXCR4
  D’Agostino,Gianluca Artinger,Marc Locati,Massimo Perez,Laurent Legler,Daniel F. Bianchi,Marco E. Rüegg,Curzio Thelen,Marcus Marchese,Adriano Rocchi,Marco B. L. Cecchinato,Valentina Uguccioni,Mariagrazia
  in Frontiers in Immunology (2020) Vol.11 pp550824
  
• Oxidation State Dependent Conformational Changes of HMGB1 Regulate the Formation of the CXCL12/HMGB1 Heterocomplex
  Fassi, E. M. A. Sgrignani, J. D'Agostino, G. Garofalo, M. Grazioso, G. Uguccioni, M. Cavalli, A.
  in Comput Struct Biotechnol J (2019) Vol.17 pp886-894
  
• Redox-Mediated Mechanisms Fuel Monocyte Responses to CXCL12/HMGB1 in Active Rheumatoid Arthritis
  Cecchinato, V. D'Agostino, G. Raeli, L. Schiraldi, M. Danelon, G. Manzo, A. Thelen, M. Ciurea, A. Bianchi, M. E. Rubartelli, A. Pitzalis, C. Uguccioni, M.
  in Front Immunol (2018) Vol.9 pp2118
  
• Chemokine Heterocomplexes and Cancer: A Novel Chapter to Be Written in Tumor Immunity
  D'Agostino, G. Cecchinato, V. Uguccioni, M.
  in Front Immunol (2018) Vol.9 pp2185
  
• Lidocaine inhibits cytoskeletal remodelling and human breast cancer cell migration
  D'Agostino, G. Saporito, A. Cecchinato, V. Borgeat, A. Anselmi, L. Uguccioni, M.
  in British Journal of Anaesthesia (2018) Vol.121 pp962-968
  
• Insight on the regulation of chemokine activities
  Cecchinato, V. Uguccioni, M.
  in J Leukoc Biol (2018) Vol.104 pp295-300
  
• Molecular Signatures of Immunity and Immunogenicity in Infection and Vaccination
  Haks, M. C. Bottazzi, B. Cecchinato, V. Del Giudice, G. Kaufmann, S. H. E. Lanzavecchia, A. Lewis, D. J. M. Maertzdorf, J. Mantovani, A. Sallusto, F. Sironi, M. Uguccioni, M. Ottenhoff, T. H. M.
  in Front Immunol (2017) Vol.8 pp1563
  
• Epithelial chemokine CXCL14 synergizes with CXCL12 via allosteric modulation of CXCR4
  Collins, P. J. McCully, M. L. Martinez-Munoz, L. Wheeldon, J. Caucheteux, S. Thelen, S. Cecchinato, V. Laufer, J. M. Purvanov, V. Monneau, Y. R. Lortat-Jacob, H. Legler, D. F. Uguccioni, M. Thelen, M. Piguet, V. Mellado, M. Moser, B.
  in FASEB J (2017) Vol.31 pp3084-3097
  
• Impairment of CCR6+ and CXCR3+ Th Cell Migration in HIV-1 Infection Is Rescued by Modulating Actin Polymerization
  Cecchinato, V. Bernasconi, E. Speck, R. F. Sauermann, U. D'Agostino, G. Danelon, G. Rezzonico Jost, T. Grassi, F. Raeli, L. Schoni-Affolter, F. Stahl-Hennig, C. Uguccioni, M. Swiss, H. I. V. Cohort Study
  in J Immunol (2016) Vol.198 pp184-195
  
• Potential of PEGylated Toll-Like Receptor 7 Ligands for Controlling Inflammation and Functional Changes in Mouse Models of Asthma and Silicosis
  Ferreira, T. P. Mariano, L. L. Ghilosso-Bortolini, R. Fernandes, A. J. Berni, M. Cecchinato, V. Uguccioni, M. Maj, R. Barberis, A. Silva, P. M. Martins, M. A.
  in Front Immunol (2016) Vol.7 pp95
  
• Chemokine interaction with synergy-inducing molecules: fine tuning modulation of cell trafficking
  Cecchinato, V. D'Agostino, G. Raeli, L.
  in J Leukoc Biol (2015) Vol.99 pp851-5
  
• Innate immune cells express IL-17A/F in acute generalized exanthematous pustulosis and generalized pustular psoriasis
  Kakeda, M. Schlapbach, C. Danelon, G. Cecchinato, V. Yawalkar, N. Uguccioni, M.
  in Arch Dermatol Res (2014) Vol.306 pp933-8