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Institute for Research in Biomedicine
Istituto di Ricerca in Biomedicina

Via Vincenzo Vela 6 - CH-6500 Bellinzona
Tel. +41 91 820 0300 - Fax +41 91 820 0302 - info [at] irb [dot] usi [dot] ch

Valentina Cecchinato, PhD

Chemokines in Immunity

Scientist

Via Vela, 6
6500 Bellinzona, Switzerland

Projects
Responses to chemokines and trafficking at mucosal sites
Publications
Oxidation State Dependent Conformational Changes of HMGB1 Regulate the Formation of the CXCL12/HMGB1 Heterocomplex
E. Fassi, J. Sgrignani, G. D'Agostino, V. Cecchinato, M. Garofalo, G. Grazioso, M. Uguccioni, A. Cavalli
in Computational and Structural Biology Journal (2019) vol. 17 pp886-894
Redox-Mediated Mechanisms Fuel Monocyte Responses to CXCL12/HMGB1 in Active Rheumatoid Arthritis
V. Cecchinato, G. D'Agostino, L. Raeli, A. Nerviani, M. Schiraldi, G. Danelon, A. Manzo, M. Thelen, A. Ciurea, M. E. Bianchi, A. Rubartelli, C. Pitzalis, M. Uguccioni
in Front Immunol (2018) vol. 9 pp2118
Chemokine Heterocomplexes and Cancer: A Novel Chapter to Be Written in Tumor Immunity
G. D'Agostino, V. Cecchinato, M. Uguccioni
in Front Immunol (2018) vol. 9 pp2185
Lidocaine inhibits cytoskeletal remodelling and human breast cancer cell migration
G. D'Agostino, A. Saporito, V. Cecchinato, Y. Silvestri, A. Borgeat, L. Anselmi, M. Uguccioni
in British Journal of Anaesthesia (2018) vol. 121 pp962-968
Insight on the regulation of chemokine activities
V. Cecchinato, M. Uguccioni
in J Leukoc Biol (2018) vol. 104 pp295-300
Molecular Signatures of Immunity and Immunogenicity in Infection and Vaccination
M. C. Haks, B. Bottazzi, V. Cecchinato, C. De Gregorio, G. Del Giudice, S. H. E. Kaufmann, A. Lanzavecchia, D. J. M. Lewis, J. Maertzdorf, A. Mantovani, F. Sallusto, M. Sironi, M. Uguccioni, T. H. M. Ottenhoff
in Front Immunol (2017) vol. 8 pp1563
Epithelial chemokine CXCL14 synergizes with CXCL12 via allosteric modulation of CXCR4
P. J. Collins, M. L. McCully, L. Martinez-Munoz, C. Santiago, J. Wheeldon, S. Caucheteux, S. Thelen, V. Cecchinato, J. M. Laufer, V. Purvanov, Y. R. Monneau, H. Lortat-Jacob, D. F. Legler, M. Uguccioni, M. Thelen, V. Piguet, M. Mellado, B. Moser
in FASEB J (2017) vol. 31 pp3084-3097
Impairment of CCR6+ and CXCR3+ Th Cell Migration in HIV-1 Infection Is Rescued by Modulating Actin Polymerization
V. Cecchinato, E. Bernasconi, R. F. Speck, M. Proietti, U. Sauermann, G. D'Agostino, G. Danelon, T. Rezzonico Jost, F. Grassi, L. Raeli, F. Schoni-Affolter, C. Stahl-Hennig, M. Uguccioni, H. I. V. Cohort Study Swiss
in J Immunol (2017) vol. 198 pp184-195
Potential of PEGylated Toll-Like Receptor 7 Ligands for Controlling Inflammation and Functional Changes in Mouse Models of Asthma and Silicosis
T. P. Ferreira, L. L. Mariano, R. Ghilosso-Bortolini, A. C. de Arantes, A. J. Fernandes, M. Berni, V. Cecchinato, M. Uguccioni, R. Maj, A. Barberis, P. M. Silva, M. A. Martins
in Front Immunol (2016) vol. 7 pp95
Chemokine interaction with synergy-inducing molecules: fine tuning modulation of cell trafficking
V. Cecchinato, G. D'Agostino, L. Raeli, M. Uguccioni
in J Leukoc Biol (2016) vol. 99 pp851-5
Innate immune cells express IL-17A/F in acute generalized exanthematous pustulosis and generalized pustular psoriasis
M. Kakeda, C. Schlapbach, G. Danelon, M. M. Tang, V. Cecchinato, N. Yawalkar, M. Uguccioni
in Arch Dermatol Res (2014) vol. 306 pp933-8