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Institute for Research in Biomedicine
Istituto di Ricerca in Biomedicina

Via Vincenzo Vela 6 - CH-6500 Bellinzona
Tel. +41 91 820 0300 - Fax +41 91 820 0302 - info [at] irb [dot] usi [dot] ch

Sylvia Thelen, PhD

Signal Transduction


Via Vela, 6
6500 Bellinzona, Switzerland

Sylvia Thelen
CCL20 is a novel ligand for the scavenging atypical chemokine receptor 4
C. Matti, G. D'Uonnolo, M. Artinger, S. Melgrati, A. Salnikov, S. Thelen, V. Purvanov, T. D. Strobel, L. Spannagel, M. Thelen, D. F. Legler
in J Leukoc Biol (2020) vol. 107 pp1137-1154
Characterization of a chimeric chemokine as a specific ligand for ACKR3
R. Ameti, S. Melgrati, E. Radice, E. Cameroni, E. Hub, S. Thelen, A. Rot, M. Thelen
in J Leukoc Biol (2018) vol. 104 pp391-400
ACKR3 expression on diffuse large B cell lymphoma is required for tumor spreading and tissue infiltration
V. Puddinu, S. Casella, E. Radice, S. Thelen, S. Dirnhofer, F. Bertoni, M. Thelen
in Oncotarget (2017) vol. 8 pp85068-85084
Epithelial chemokine CXCL14 synergizes with CXCL12 via allosteric modulation of CXCR4
P. J. Collins, M. L. McCully, L. Martinez-Munoz, C. Santiago, J. Wheeldon, S. Caucheteux, S. Thelen, V. Cecchinato, J. M. Laufer, V. Purvanov, Y. R. Monneau, H. Lortat-Jacob, D. F. Legler, M. Uguccioni, M. Thelen, V. Piguet, M. Mellado, B. Moser
in FASEB J (2017) vol. 31 pp3084-3097
Structural basis for chemokine recognition by a G protein-coupled receptor and implications for receptor activation
J. J. Ziarek, A. B. Kleist, N. London, B. Raveh, N. Montpas, J. Bonneterre, G. St-Onge, C. J. DiCosmo-Ponticello, C. A. Koplinski, I. Roy, B. Stephens, S. Thelen, C. T. Veldkamp, F. D. Coffman, M. C. Cohen, M. B. Dwinell, M. Thelen, F. C. Peterson, N. Heveker, B. F. Volkman
in Sci Signal (2017) vol. 10
Association of eukaryotic translation initiation factor eIF2B with fully solubilized CXCR4
E. Palmesino, T. Apuzzo, S. Thelen, B. Mueller, H. Langen, M. Thelen
in J Leukoc Biol (2016) vol. 99 pp971-8
Complementary methods provide evidence for the expression of CXCR7 on human B cells
M. L. Humpert, M. Tzouros, S. Thelen, A. Bignon, A. Levoye, F. Arenzana-Seisdedos, K. Balabanian, F. Bachelerie, H. Langen, M. Thelen
in Proteomics (2012) vol. 12 pp1938-48
CCR2 Acts as Scavenger for CCL2 during Monocyte Chemotaxis
S. Volpe, E. Cameroni, B. Moepps, S. Thelen, T. Apuzzo, M. Thelen
in PLoS One (2012) vol. 7 ppe37208
The guanine-nucleotide-exchange factor P-Rex1 is activated by protein phosphatase 1alpha
M. A. Barber, A. Hendrickx, M. Beullens, H. Ceulemans, D. Oxley, S. Thelen, M. Thelen, M. Bollen, H. C. Welch
in Biochem J (2012) vol. 443 pp173-83
Cxcl12 evolution - subfunctionalization of a ligand through altered interaction with the chemokine receptor
B. Boldajipour, M. Doitsidou, K. Tarbashevich, C. Laguri, S. R. Yu, J. Ries, K. Dumstrei, S. Thelen, J. Dorries, E. M. Messerschmidt, M. Thelen, P. Schwille, M. Brand, H. Lortat-Jacob, E. Raz
in Development (2011) vol. 138 pp2909-14
Polarization of migrating monocytic cells is independent of PI 3-kinase activity
S. Volpe, S. Thelen, T. Pertel, M. J. Lohse, M. Thelen
in PLoS One (2010) vol. 5 ppe10159
CXCR7, CXCR4 and CXCL12: an eccentric trio?
M. Thelen, S. Thelen
in J Neuroimmunol (2008) vol. 198 pp9-13
Membrane translocation of P-Rex1 is mediated by G protein betagamma subunits and phosphoinositide 3-kinase
M. A. Barber, S. Donald, S. Thelen, K. E. Anderson, M. Thelen, H. C. Welch
in J Biol Chem (2007) vol. 282 pp29967-76
Unusual chemokine receptor antagonism involving a mitogen-activated protein kinase pathway
P. Ogilvie, S. Thelen, B. Moepps, P. Gierschik, A. C. da Silva Campos, M. Baggiolini, M. Thelen
in J Immunol (2004) vol. 172 pp6715-22
Constitutive expression of stromal derived factor-1 by mucosal epithelia and its role in HIV transmission and propagation
W. W. Agace, A. Amara, A. I. Roberts, J. L. Pablos, S. Thelen, M. Uguccioni, X. Y. Li, J. Marsal, F. Arenzana-Seisdedos, T. Delaunay, E. C. Ebert, B. Moser, C. M. Parker
in Curr Biol (2000) vol. 10 pp325-8