Publications - IRB USI

Publications

Phase separation properties of RPA combine high-affinity ssDNA binding with dynamic condensate functions at telomeres
Spegg, V. Panagopoulos, A. Stout, M. Krishnan, A. Reginato, G. Imhof, R. Roschitzki, B. Cejka, P. Altmeyer, M.
in Nat Struct Mol Biol (2023) Vol. pp
Esmethadone-HCl (REL-1017): a promising rapid antidepressant
Fava, M. Stahl, S. M. De Martin, S. Mattarei, A. Bettini, E. Comai, S. Alimonti, A. Bifari, F. Pani, L. Folli, F. Guidetti, C. Furlan, A. Sgrignani, J. Locatelli, P. Cavalli, A. O'Gorman, C. Traversa, S. Inturrisi, C. E. Pappagallo, M. Manfredi, P. L.
in Eur Arch Psychiatry Clin Neurosci (2023) Vol. pp
Sequence and chromatin features guide DNA double-strand break resection initiation
Gnugge, R. Reginato, G. Cejka, P. Symington, L. S.
in Mol Cell (2023) Vol. pp
Autoantibodies against chemokines post-SARS-CoV-2 infection correlate with disease course
Muri, J. Cecchinato, V. Cavalli, A. Shanbhag, A. A. Matkovic, M. Biggiogero, M. Maida, P. A. Moritz, J. Toscano, C. Ghovehoud, E. Furlan, R. Barbic, F. Voza, A. De Nadai, G. Cervia, C. Zurbuchen, Y. Taeschler, P. Murray, L. A. Danelon-Sargenti, G. Moro, S. Gong, T. Piffaretti, P. Bianchini, F. Crivelli, V. Podesvova, L. Pedotti, M. Jarrossay, D. Sgrignani, J. Thelen, S. Uhr, M. Bernasconi, E. Rauch, A. Manzo, A. Ciurea, A. Rocchi, M. B. L. Varani, L. Moser, B. Bottazzi, B. Thelen, M. Fallon, B. A. Boyman, O. Mantovani, A. Garzoni, C. Franzetti-Pellanda, A. Uguccioni, M. Robbiani, D. F.
in Nat Immunol (2023) Vol. pp
Apolipoprotein E induces pathogenic senescent-like myeloid cells in prostate cancer
Bancaro, N. Cali, B. Troiani, M. Elia, A. R. Arzola, R. A. Attanasio, G. Lai, P. Crespo, M. Gurel, B. Pereira, R. Guo, C. Mosole, S. Brina, D. D'Ambrosio, M. Pasquini, E. Spataro, C. Zagato, E. Rinaldi, A. Pedotti, M. Di Lascio, S. Meani, F. Montopoli, M. Ferrari, M. Gallina, A. Varani, L. Pereira Mestre, R. Bolis, M. Gillessen Sommer, S. de Bono, J. Calcinotto, A. Alimonti, A.
in Cancer Cell (2023) Vol. pp
Human IL-23 is essential for IFN-gamma-dependent immunity to mycobacteria
Philippot, Q. Ogishi, M. Bohlen, J. Puchan, J. Arias, A. A. Nguyen, T. Martin-Fernandez, M. Conil, C. Rinchai, D. Momenilandi, M. Mahdaviani, S. A. Keramatipour, M. Rosain, J. Yang, R. Khan, T. Neehus, A. L. Materna, M. Han, J. E. Peel, J. Mele, F. Weisshaar, M. Jovic, S. Bastard, P. Levy, R. Le Voyer, T. Zhang, P. Maglorius Renkilaraj, M. R. L. Arango-Franco, C. A. Pelham, S. Seeleuthner, Y. Pochon, M. Ata, M. M. A. Al Ali, F. Migaud, M. Soudee, C. Kochetkov, T. Molitor, A. Carapito, R. Bahram, S. Boisson, B. Fieschi, C. Mansouri, D. Marr, N. Okada, S. Shahrooei, M. Parvaneh, N. Chavoshzadeh, Z. Cobat, A. Bogunovic, D. Abel, L. Tangye, S. G. Ma, C. S. Beziat, V. Sallusto, F. Boisson-Dupuis, S. Bustamante, J. Casanova, J. L. Puel, A.
in Sci Immunol (2023) Vol.8 ppeabq5204
Antibodies Produced by CLL Phenotype B Cells in Patients With Myasthenia Gravis Are Not Directed Against Neuromuscular Endplates
Ingelfinger, F. Kramer, M. Lutz, M. Widmer, C. C. Piccoli, L. Kreutmair, S. Wertheimer, T. Woodhall, M. Waters, P. Sallusto, F. Lanzavecchia, A. Mundt, S. Becher, B. Schreiner, B.
in Neurol Neuroimmunol Neuroinflamm (2023) Vol.10 pp
Proteasomal and Lysosomal Degradation of Misfolded Proteins From the Endoplasmic Reticulum
Molinari, M.
in Encyclopedia of Cell Biology (2023) Vol.2 pp702-710
PLK1 regulates CtIP and DNA2 interplay in long-range DNA end resection
Ceppi, I. Cannavo, E. Bret, H. Camarillo, R. Vivalda, F. Thakur, R. S. Romero-Franco, A. Sartori, A. A. Huertas, P. Guerois, R. Cejka, P.
in Genes Dev (2023) Vol. pp
Human neutralizing antibodies to cold linear epitopes and subdomain 1 of the SARS-CoV-2 spike glycoprotein
Bianchini, F. Crivelli, V. Abernathy, M. E. Guerra, C. Palus, M. Muri, J. Marcotte, H. Piralla, A. Pedotti, M. De Gasparo, R. Simonelli, L. Matkovic, M. Toscano, C. Biggiogero, M. Calvaruso, V. Svoboda, P. Cervantes Rincon, T. Fava, T. Podesvova, L. Shanbhag, A. A. Celoria, A. Sgrignani, J. Stefanik, M. Honig, V. Pranclova, V. Michalcikova, T. Prochazka, J. Guerrini, G. Mehn, D. Ciabattini, A. Abolhassani, H. Jarrossay, D. Uguccioni, M. Medaglini, D. Pan-Hammarstrom, Q. Calzolai, L. Fernandez, D. Baldanti, F. Franzetti-Pellanda, A. Garzoni, C. Sedlacek, R. Ruzek, D. Varani, L. Cavalli, A. Barnes, C. O. Robbiani, D. F.
in Sci Immunol (2023) Vol. ppeade0958
Tracking unlabeled cancer cells imaged with low resolution in wide migration chambers via U-NET class-1 probability (pseudofluorescence)
Antonello, P. Morone, D. Pirani, E. Uguccioni, M. Thelen, M. Krause, R. Pizzagalli, D. U.
in J Biol Eng (2023) Vol.17 pp5
Eomesodermin-expressing type 1 regulatory (EOMES(+) Tr1)-like T cells: Basic biology and role in immune-mediated diseases
Geginat, J. Vasco, C. Gruarin, P. Bonnal, R. Rossetti, G. Silvestri, Y. Carelli, E. Pulvirenti, N. Scantamburlo, M. Moschetti, G. Clemente, F. Grassi, F. Monticelli, S. Pagani, M. Abrignani, S.
in Eur J Immunol (2023) Vol. ppe2149775
ACKR3 promotes CXCL12/CXCR4-mediated cell-to-cell-induced lymphoma migration through LTB4 production
Antonello, P. Pizzagalli, D. U. Foglierini, M. Melgrati, S. Radice, E. Thelen, S. Thelen, M.
in Front Immunol (2023) Vol.13 pp1067885
Macrophages and glia are the dominant P2X7-expressing cell types in the gut nervous system – no evidence for a role of neuronal P2X7 receptors in colitis
Jooss, T. Zhang, J. Zimmer, B. Rezzonico-Jost, T. Rissiek, B. Felipe Pelczar, P. Seehusen, F. Koch-Nolte, F. Magnus, T. Zierler, S. Huber, S. Schemann, M. Grassi, F. Nicke, A.
in Mucosal Immunol (2023) Vol. pp
A monoclonal antibody targeting nonjunctional claudin-1 inhibits fibrosis in patient-derived models by modulating cell plasticity
Roehlen, N. Saviano, A. El Saghire, H. Crouchet, E. Nehme, Z. Del Zompo, F. Juhling, F. Oudot, M. A. Durand, S. C. Duong, F. H. T. Cherradi, S. Gonzalez Motos, V. Almeida, N. Ponsolles, C. Heydmann, L. Ostyn, T. Lallement, A. Pessaux, P. Felli, E. Cavalli, A. Sgrignani, J. Thumann, C. Koutsopoulos, O. Fuchs, B. C. Hoshida, Y. Hofmann, M. Vyberg, M. Viuff, B. M. Galsgaard, E. D. Elson, G. Toso, A. Meyer, M. Iacone, R. Schweighoffer, T. Teixeira, G. Moll, S. De Vito, C. Roskams, T. Davidson, I. Heide, D. Heikenwalder, M. Zeisel, M. B. Lupberger, J. Mailly, L. Schuster, C. Baumert, T. F.
in Sci Transl Med (2022) Vol.14 ppeabj4221
WRN helicase and mismatch repair complexes independently and synergistically disrupt cruciform DNA structures
Mengoli, V. Ceppi, I. Sanchez, A. Cannavo, E. Halder, S. Scaglione, S. Gaillard, P. H. McHugh, P. J. Riesen, N. Pettazzoni, P. Cejka, P.
in EMBO J (2022) Vol. ppe111998
Selective involvement of UGGT variant: UGGT2 in protecting mouse embryonic fibroblasts from saturated lipid-induced ER stress
Hung, H. H. Nagatsuka, Y. Solda, T. Kodali, V. K. Iwabuchi, K. Kamiguchi, H. Kano, K. Matsuo, I. Ikeda, K. Kaufman, R. J. Molinari, M. Greimel, P. Hirabayashi, Y.
in Proc Natl Acad Sci U S A (2022) Vol.119 ppe2214957119
Clonal composition and persistence of antigen-specific circulating T follicular helper cells
Hu, M. Notarbartolo, S. Foglierini, M. Jovic, S. Mele, F. Jarrossay, D. Lanzavecchia, A. Cassotta, A. Sallusto, F.
in Eur J Immunol (2022) Vol. pp
Longitudinal Postvaccine SARS-CoV-2 Immunoglobulin G Titers, Memory B-Cell Responses, and Risk of COVID-19 in Multiple Sclerosis Over 1 Year
Disanto, G. Galante, A. Cantu, M. Sacco, R. Mele, F. Eisler, J. J. Keller, F. Bernasconi, E. Sallusto, F. Zecca, C. Gobbi, C.
in Neurol Neuroimmunol Neuroinflamm (2022) Vol.10 pp
SARS-CoV-2 spike conformation determines plasma neutralizing activity elicited by a wide panel of human vaccines
Bowen, J. E. Park, Y. J. Stewart, C. Brown, J. T. Sharkey, W. K. Walls, A. C. Joshi, A. Sprouse, K. R. McCallum, M. Tortorici, M. A. Franko, N. M. Logue, J. K. Mazzitelli, I. G. Nguyen, A. W. Silva, R. P. Huang, Y. Low, J. S. Jerak, J. Tiles, S. W. Ahmed, K. Shariq, A. Dan, J. M. Zhang, Z. Weiskopf, D. Sette, A. Snell, G. Posavad, C. M. Iqbal, N. T. Geffner, J. Bandera, A. Gori, A. Sallusto, F. Maynard, J. A. Crotty, S. Van Voorhis, W. C. Simmerling, C. Grifantini, R. Chu, H. Y. Corti, D. Veesler, D.
in Sci Immunol (2022) Vol. ppeadf1421
Heterogeneity of tissue-resident immunity across organs and in health and disease
Arck, P. C. Sallusto, F.
in Semin Immunopathol (2022) Vol. pp
Subcapsular sinus macrophages promote melanoma metastasis to the sentinel lymph nodes via an IL-1alpha-STAT3 axis
Virgilio, T. Bordini, J. Cascione, L. Sartori, G. Latino, I. Molina Romero, D. Leoni, C. Akhmedov, M. Rinaldi, A. Arribas, A. J. Morone, D. Seyed Jafari, S. M. Bersudsky, M. Ottolenghi, A. Kwee, I. Chiaravalli, A. M. Sessa, F. Hunger, R. E. Bruno, A. Mortara, L. Voronov, E. Monticelli, S. Apte, R. N. Bertoni, F. Gonzalez, S. F.
in Cancer Immunol Res (2022) Vol.10 pp1525-1541
Concomitant deletion of Ptpn6 and Ptpn11 in T cells fails to improve anticancer responses
Ventura, P. M. O. Gakovic, M. Fischer, B. A. Spinelli, L. Rota, G. Pathak, S. Khameneh, H. J. Zenobi, A. Thomson, S. Birchmeier, W. Cantrell, D. A. Guarda, G.
in EMBO Rep (2022) Vol. ppe55399
Maturation of SARS-CoV-2 Spike-specific memory B cells drives resilience to viral escape
Marzi, R. Bassi, J. Silacci-Fregni, C. Bartha, I. Muoio, F. Culap, K. Sprugasci, N. Lombardo, G. Saliba, C. Cameroni, E. Cassotta, A. Low, J. S. Walls, A. C. McCallum, M. Tortorici, M. A. Bowen, J. E. Dellota, E. A. Dillen, J. R. Czudnochowski, N. Pertusini, L. Terrot, T. Lepori, V. Tarkowski, M. Riva, A. Biggiogero, M. Pellanda, A. F. Garzoni, C. Ferrari, P. Ceschi, A. Giannini, O. Havenar-Daughton, C. Telenti, A. Arvin, A. Virgin, H. W. Sallusto, F. Veesler, D. Lanzavecchia, A. Corti, D. Piccoli, L.
in iScience (2022) Vol.26 pp105726
Double-stranded DNA binding function of RAD51 in DNA protection and its regulation by BRCA2
Halder, S. Sanchez, A. Ranjha, L. Reginato, G. Ceppi, I. Acharya, A. Anand, R. Cejka, P.
in Mol Cell (2022) Vol. pp
Different classes of genomic inserts contribute to human antibody diversity
Lebedin, M. Foglierini, M. Khorkova, S. Vazquez Garcia, C. Ratswohl, C. Davydov, A. N. Turchaninova, M. A. Daubenberger, C. Chudakov, D. M. Lanzavecchia, A. de la Rosa, K.
in Proc Natl Acad Sci U S A (2022) Vol.119 ppe2205470119
CEMIP (HYBID, KIAA1199): Structure, function and expression in health and disease
Spataro, S. Guerra, C. Cavalli, A. Sgrignani, J. Sleeman, J. Poulain, L. Boland, A. Scapozza, L. Moll, S. Prunotto, M.
in FEBS J (2022) Vol. pp
PDIA3 epitope-driven immune autoreactivity contributes to hepatic damage in type 2 diabetes
Clement, C. C. Osan, J. Buque, A. Nanaware, P. P. Chang, Y. C. Perino, G. Shetty, M. Yamazaki, T. Tsai, W. L. Urbanska, A. M. Calvo-Calle, J. M. Ramsamooj, S. Vergani, D. Mieli-Vergani, G. Terziroli Beretta-Piccoli, B. Gadina, M. Montagna, C. Goncalves, M. D. Sallusto, F. Galluzzi, L. Soni, R. K. Stern, L. J. Santambrogio, L.
in Sci Immunol (2022) Vol.7 ppeabl3795
Pharmacological Comparative Characterization of REL-1017 (Esmethadone-HCl) and Other NMDAR Channel Blockers in Human Heterodimeric N-Methyl-D-Aspartate Receptors
Bettini, E. Stahl, S. M. De Martin, S. Mattarei, A. Sgrignani, J. Carignani, C. Nola, S. Locatelli, P. Pappagallo, M. Inturrisi, C. E. Bifari, F. Cavalli, A. Alimonti, A. Pani, L. Fava, M. Traversa, S. Folli, F. Manfredi, P. L.
in Pharmaceuticals (Basel) (2022) Vol.15 pp
Discovery of anti-Formin-like 1 protein (FMNL1) antibodies in membranous nephropathy and other glomerular diseases
Bruschi, M. Cavalli, A. Moll, S. Candiano, G. Scapozza, L. Patel, J. J. Tan, J. C. Lo, K. C. Angeletti, A. Ghiggeri, G. M. Prunotto, M.
in Sci Rep (2022) Vol.12 pp13659
A conformational switch controlling the toxicity of the prion protein
Frontzek, K. Bardelli, M. Senatore, A. Henzi, A. Reimann, R. R. Bedir, S. Marino, M. Hussain, R. Jurt, S. Meisl, G. Pedotti, M. Mazzola, F. Siligardi, G. Zerbe, O. Losa, M. Knowles, T. Lakkaraju, A. Zhu, C. Schwarz, P. Hornemann, S. Holt, M. G. Simonelli, L. Varani, L. Aguzzi, A.
in Nat Struct Mol Biol (2022) Vol.29 pp831-840
The function of Wtap in N(6)-adenosine methylation of mRNAs controls T cell receptor signaling and survival of T cells
Ito-Kureha, T. Leoni, C. Borland, K. Cantini, G. Bataclan, M. Metzger, R. N. Ammann, G. Krug, A. B. Marsico, A. Kaiser, S. Canzar, S. Feske, S. Monticelli, S. Konig, J. Heissmeyer, V.
in Nat Immunol (2022) Vol. pp
ACE2-binding exposes the SARS-CoV-2 fusion peptide to broadly neutralizing coronavirus antibodies
Low, J. S. Jerak, J. Tortorici, M. A. McCallum, M. Pinto, D. Cassotta, A. Foglierini, M. Mele, F. Abdelnabi, R. Weynand, B. Noack, J. Montiel-Ruiz, M. Bianchi, S. Benigni, F. Sprugasci, N. Joshi, A. Bowen, J. E. Stewart, C. Rexhepaj, M. Walls, A. C. Jarrossay, D. Morone, D. Paparoditis, P. Garzoni, C. Ferrari, P. Ceschi, A. Neyts, J. Purcell, L. A. Snell, G. Corti, D. Lanzavecchia, A. Veesler, D. Sallusto, F.
in Science (2022) Vol. ppeabq2679
Strand annealing and motor driven activities of SMARCAL1 and ZRANB3 are stimulated by RAD51 and the paralog complex
Halder, S. Ranjha, L. Taglialatela, A. Ciccia, A. Cejka, P.
in Nucleic Acids Res (2022) Vol. pp
Clonal structure, stability and dynamics of human memory B cells and circulating plasmablasts
Phad, G. E. Pinto, D. Foglierini, M. Akhmedov, M. Rossi, R. L. Malvicini, E. Cassotta, A. Fregni, C. S. Bruno, L. Sallusto, F. Lanzavecchia, A.
in Nat Immunol (2022) Vol. pp

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