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FOXC2 controls adult lymphatic endothelial specialization, function, and gut lymphatic barrier preventing multiorgan failure
Gonzalez-Loyola, A. Bovay, E. Kim, J. Lozano, T. W. Sabine, A. Renevey, F. Arroz-Madeira, S. Rapin, A. Wypych, T. P. Rota, G. Durot, S. Velin, D. Marsland, B. Guarda, G. Delorenzi, M. Zamboni, N. Luther, S. A. Petrova, T. V.
in Sci Adv (2021) Vol.7 ppeabf4335
Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs
Xu, K. Wang, Y. Shen, C. H. Chen, Y. Zhang, B. Liu, K. Tsybovsky, Y. Wang, S. Farney, S. K. Gorman, J. Stephens, T. Verardi, R. Yang, Y. Zhou, T. Chuang, G. Y. Lanzavecchia, A. Piccoli, L. Kwong, P. D.
in Nat Commun (2021) Vol.12 pp4226
The P2X7 Receptor in Tumor Immunity
Grassi, F. De Ponte Conti, B.
in Front Cell Dev Biol (2021) Vol.9 pp694831
Mapping mutations to the SARS-CoV-2 RBD that escape binding by different classes of antibodies
Greaney, A. J. Starr, T. N. Barnes, C. O. Weisblum, Y. Schmidt, F. Caskey, M. Gaebler, C. Cho, A. Agudelo, M. Finkin, S. Wang, Z. Poston, D. Muecksch, F. Hatziioannou, T. Bieniasz, P. D. Robbiani, D. F. Nussenzweig, M. C. Bjorkman, P. J. Bloom, J. D.
in Nat Commun (2021) Vol.12 pp4196
EZH2-induced lysine K362 methylation enhances TMPRSS2-ERG oncogenic activity in prostate cancer
Zoma, M. Curti, L. Shinde, D. Albino, D. Mitra, A. Sgrignani, J. Mapelli, S. N. Sandrini, G. Civenni, G. Merulla, J. Chiorino, G. Kunderfranco, P. Cacciatore, A. Kokanovic, A. Rinaldi, A. Cavalli, A. Catapano, C. V. Carbone, G. M.
in Nat Commun (2021) Vol.12 pp4147
High Th2 cytokine levels and upper airway inflammation in human inherited T-bet deficiency
Yang, R. Weisshaar, M. Mele, F. Benhsaien, I. Dorgham, K. Han, J. Croft, C. A. Notarbartolo, S. Rosain, J. Bastard, P. Puel, A. Fleckenstein, B. Glimcher, L. H. Di Santo, J. P. Ma, C. S. Gorochov, G. Bousfiha, A. Abel, L. Tangye, S. G. Casanova, J. L. Bustamante, J. Sallusto, F.
in J Exp Med (2021) Vol.218 ppe20202726
Inhibition of MRN activity by a telomere protein motif
Khayat, F. Cannavo, E. Alshmery, M. Foster, W. R. Chahwan, C. Maddalena, M. Smith, C. Oliver, A. W. Watson, A. T. Carr, A. M. Cejka, P. Bianchi, A.
in Nat Commun (2021) Vol.12 pp3856
N-glycan processing selects ERAD-resistant misfolded proteins for ER-to-lysosome-associated degradation
Fregno, I. Fasana, E. Solda, T. Galli, C. Molinari, M.
in EMBO J (2021) Vol. ppe107240
Machine learning analyses of antibody somatic mutations predict immunoglobulin light chain toxicity
Garofalo, M. Piccoli, L. Romeo, M. Barzago, M. M. Ravasio, S. Foglierini, M. Matkovic, M. Sgrignani, J. De Gasparo, R. Prunotto, M. Varani, L. Diomede, L. Michielin, O. Lanzavecchia, A. Cavalli, A.
in Nature Communications (2021) Vol.12 pp3532
A Comprehensive Evaluation of the Relationship Between Different IgG and IgA Anti-Modified Protein Autoantibodies in Rheumatoid Arthritis
Gronwall, C. Liljefors, L. Bang, H. Hensvold, A. H. Hansson, M. Mathsson-Alm, L. Israelsson, L. Joshua, V. Svard, A. Stalesen, R. Titcombe, P. J. Steen, J. Piccoli, L. Sherina, N. Clavel, C. Svenungsson, E. Gunnarsson, I. Saevarsdottir, S. Kastbom, A. Serre, G. Alfredsson, L. Malmstrom, V. Ronnelid, J. Catrina, A. I. Lundberg, K. Klareskog, L.
in Front Immunol (2021) Vol.12 pp627986
Molecular basis of the dual role of the Mlh1-Mlh3 endonuclease in MMR and in meiotic crossover formation
Dai, J. Sanchez, A. Adam, C. Ranjha, L. Reginato, G. Chervy, P. Tellier-Lebegue, C. Andreani, J. Guerois, R. Ropars, V. Le Du, M. H. Maloisel, L. Martini, E. Legrand, P. Thureau, A. Cejka, P. Borde, V. Charbonnier, J. B.
in Proc Natl Acad Sci U S A (2021) Vol.118 ppe2022704118
HMGB1 promotes CXCL12-dependent egress of murine B cells from Peyer’s patches in homeostasis
Spagnuolo, L. Puddinu, V. Boss, N. Spinetti, T. Oberson, A. Widmer, J. Mottas, I. Hotz, C. Bianchi, M. E. Uguccioni, M. Bourquin, C.
in Eur J Immunol (2021) Vol. pp
A rationally designed oral vaccine induces immunoglobulin A in the murine gut that directs the evolution of attenuated Salmonella variants
Diard, M. Bakkeren, E. Lentsch, V. Rocker, A. Bekele, N. A. Hoces, D. Aslani, S. Arnoldini, M. Bohi, F. Schumann-Moor, K. Adamcik, J. Piccoli, L. Lanzavecchia, A. Stadtmueller, B. M. Donohue, N. van der Woude, M. W. Hockenberry, A. Viollier, P. H. Falquet, L. Wuthrich, D. Bonfiglio, F. Loverdo, C. Egli, A. Zandomeneghi, G. Mezzenga, R. Holst, O. Meier, B. H. Hardt, W. D. Slack, E.
in Nat Microbiol (2021) Vol.6 pp830-841
Endoplasmic Reticulum (ER) and ER-Phagy
Loi, M. Marazza, A. Molinari, M.
in Prog Mol Subcell Biol (2021) Vol.59 pp99-114
Clonal analysis of immunodominance and cross-reactivity of the CD4 T cell response to SARS-CoV-2
Low, J. S. Vaqueirinho, D. Mele, F. Foglierini, M. Jerak, J. Perotti, M. Jarrossay, D. Jovic, S. Perez, L. Cacciatore, R. Terrot, T. Pellanda, A. F. Biggiogero, M. Garzoni, C. Ferrari, P. Ceschi, A. Lanzavecchia, A. Sallusto, F. Cassotta, A.
in Science (2021) Vol.372 pp1336-1341

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