An Unbiased Screen for Human Cytomegalovirus Identifies Neuropilin-2 as a Central Viral Receptor Martinez-Martin, N. Marcandalli, J. Huang, C. S. Perotti, M. Foglierini, M. Ho, H. Dosey, A. M. Shriver, S. Payandeh, J. Leitner, A. Lanzavecchia, A. Perez, L. Ciferri, C. in Cell (2018) Vol.174 pp1158-1171 * L. Perez and C. Ciferri contributed equally; N M-M, LP and CC are co-corresponding authors
A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein Tan, J. Sack, B. K. Oyen, D. Piccoli, L. Barbieri, S. Foglierini, M. Fregni, C. S. Marcandalli, J. Jongo, S. Abdulla, S. Perez, L. Corradin, G. Varani, L. Sallusto, F. Sim, B. K. L. Hoffman, S. L. Kappe, S. H. I. Daubenberger, C. Wilson, I. A. Lanzavecchia, A. in Nat Med (2018) Vol.24 pp401-407 * Tan J., Sack B. K., Oyen D., Zenklusen I., Piccoli L. contributed equally to this work.
A Human Bi-specific Antibody against Zika Virus with High Therapeutic Potential Wang, J. Bardelli, M. Espinosa, D. A. Ng, T. S. Bianchi, S. Simonelli, L. Lim, E. X. Y. Foglierini, M. Zatta, F. Jaconi, S. Beltramello, M. Cameroni, E. Fibriansah, G. Shi, J. Barca, T. Pagani, I. Rubio, A. Broccoli, V. Vicenzi, E. Graham, V. Pullan, S. Dowall, S. Hewson, R. Jurt, S.Zerbe, O. Stettler, K. Lanzavecchia, A. Sallusto, F. Cavalli, A. in Cell (2017) Vol.171 pp229-241 e15 * J. Wang and M. Bardelli contributed equally ; S-M Lok, L.Varani and D. Corti contributed equally.
Public antibodies to malaria antigens generated by two LAIR1 insertion modalities Pieper, K. Tan, J. Piccoli, L. Foglierini, M. Barbieri, S. Chen, Y. Silacci-Fregni, C. Wolf, T. Jarrossay, D. Anderle, M. Abdi, A. Ndungu, F. M. Doumbo, O. K. Traore, B. Tran, T. M. Jongo, S. Zenklusen, I. Crompton, P. D. Daubenberger, C. Bull, P. C. Sallusto, F. Lanzavecchia, A. in Nature (2017) Vol.548 pp597-601 * Pieper K., Tan J., Piccoli, L. contributed equally to this work.
Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes Kallewaard, N. L. Corti, D. Collins, P. J. McAuliffe, J. M. Benjamin, E. Wachter-Rosati, L. Palmer-Hill, F. J. Yuan, A. Q. Walker, P. A. Vorlaender, M. K. Bianchi, S. Guarino, B. De Marco, A. Vanzetta, F. Agatic, G. Foglierini, M. Pinna, D. Fernandez-Rodriguez, B. Fruehwirth, A. Silacci, C. Ogrodowicz, R. W. Martin, S. R. Sallusto, F. Suzich, J. A.Lanzavecchia, A. Zhu, Q. Gamblin, S. J. Skehel, J. J. in Cell (2016) Vol.166 pp596-608
Specificity, cross-reactivity and function of antibodies elicited by Zika virus infection Stettler, K. Beltramello, M. Espinosa, D. A. Cassotta, A. Bianchi, S. Vanzetta, F. Minola, A. Jaconi, S. Mele, F. Foglierini, M. Pedotti, M. Simonelli, L. Dowall, S. Atkinson, B. Percivalle, E. Simmons, C. P. Varani, L. Blum, J. Baldanti, F. Cameroni, E. Hewson, R. Harris, E. Lanzavecchia, A. Sallusto, F.Corti, D. in Science (2016) Vol.353 pp823-6 K. S and M. B contributed equally to this work; D. A. E. ; V. G. ; A. C. ; S. B. and F. V contributed equally to this work; F. S. and D. C contributed equally to this work and are co-corresponding authors.
Platelet-derived growth factor-alpha receptor is the cellular receptor for human cytomegalovirus gHgLgO trimer Kabanova, A. Marcandalli, J. Zhou, T. Baxa, U. Tsybovsky, Y. Lilleri, D. Silacci-Fregni, C. Foglierini, M. Fernandez-Rodriguez, B. M. Druz, A. Zhang, B. Geiger, R. Pagani, M. Sallusto, F. Kwong, P. D. Corti, D. Lanzavecchia, A. Perez, L. in Nat Microbiol (2016) Vol.1 pp16082 Anna Kabanova, Jessica Marcandalli, Tongqing Zhou equally contributed to this work; Antonio Lanzavecchia1and Laurent Perez jointly supervised this work.
Development of broad-spectrum human monoclonal antibodies for rabies post-exposure prophylaxis De Benedictis, P. Minola, A. Rota Nodari, E. Zecchin, B. Salomoni, A. Foglierini, M. Agatic, G. Vanzetta, F. Lavenir, R. Lepelletier, A. Bentley, E. Weiss, R. Cattoli, G. Capua, I. Sallusto, F. Wright, E. Lanzavecchia, A. Bourhy, H. Corti, D. in EMBO Mol Med (2016) Vol.8 pp407-21 Paola De Benedictis and Andrea Minola equally contributed to this work.
A LAIR1 insertion generates broadly reactive antibodies against malaria variant antigens Tan, J. Pieper, K. Piccoli, L. Foglierini, M. Geiger, R. Tully, C. M. Jarrossay, D. Ndungu, F. M. Wambua, J. Bejon, P. Fregni, C. S. Fernandez-Rodriguez, B. Barbieri, S. Bianchi, S. Marsh, K. Thathy, V. Corti, D. Sallusto, F. Bull, P. Lanzavecchia, A. in Nature (2016) Vol.529 pp105-9 Joshua Tan, Kathrin Pieper, Luca Piccoli equally contributed to this work and Peter Bull and Antonio Lanzavecchia jointly supervised this work.
Prophylactic and postexposure efficacy of a potent human monoclonal antibody against MERS coronavirus Corti, D. Zhao, J. Pedotti, M. Agnihothram, S. Fett, C. Fernandez-Rodriguez, B. Foglierini, M. Agatic, G. Vanzetta, F. Gopal, R. Langrish, C. J. Barrett, N. A. Sallusto, F. Baric, R. S. Varani, L. Zambon, M. Perlman, S. Lanzavecchia, A. in Proc Natl Acad Sci U S A (2015) Vol.112 pp10473-8 D.C. and J.Z. contributed equally to this work.
Rapid development of broadly influenza neutralizing antibodies through redundant mutations Pappas, L. Foglierini, M. Piccoli, L. Turrini, F. Silacci, C. Fernandez-Rodriguez, B. Agatic, G. Giacchetto-Sasselli, I. Pellicciotta, G. Sallusto, F. Zhu, Q. Vicenzi, E. Corti, D. Lanzavecchia, A. in Nature (2014) Vol.516 pp418-22 Davide Corti and Antonio Lanzavecchia equally contributed to this work.