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Institute for Research in Biomedicine
Istituto di Ricerca in Biomedicina

Via Vincenzo Vela 6 - CH-6500 Bellinzona
Tel. +41 91 820 0300 - Fax +41 91 820 0302 - info [at] irb [dot] usi [dot] ch



Insight on the regulation of chemokine activities
V. Cecchinato, M. Uguccioni
in J Leukoc Biol (2018)

Modulation of innate and adaptive immunity by P2X ion channels
F. Di Virgilio, A. C. Sarti, F. Grassi
in Curr Opin Immunol (2018) vol. 52 pp51-59

Shp-2 Is Dispensable for Establishing T Cell Exhaustion and for PD-1 Signaling In Vivo
G. Rota, C. Niogret, A. T. Dang, C. R. Barros, N. P. Fonta, F. Alfei, L. Morgado, D. Zehn, W. Birchmeier, E. Vivier, G. Guarda
in Cell Rep (2018) vol. 23 pp39-49

Characterization of a chimeric chemokine as a specific ligand for ACKR3
R. Ameti, S. Melgrati, E. Radice, E. Cameroni, E. Hub, S. Thelen, A. Rot, M. Thelen
in J Leukoc Biol (2018)

A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein
J. Tan, B. K. Sack, D. Oyen, I. Zenklusen, L. Piccoli, S. Barbieri, M. Foglierini, C. S. Fregni, J. Marcandalli, S. Jongo, S. Abdulla, L. Perez, G. Corradin, L. Varani, F. Sallusto, B. K. L. Sim, S. L. Hoffman, S. H. I. Kappe, C. Daubenberger, I. A. Wilson, A. Lanzavecchia
in Nat Med (2018)

Highly specific targeting of human acute myeloid leukaemia cells using pharmacologically active nanoconjugates
I. M. Yasinska, G. Ceccone, I. Ojea-Jimenez, J. Ponti, R. Hussain, G. Siligardi, S. M. Berger, E. Fasler-Kan, M. Bardelli, L. Varani, W. Fiedler, J. Wellbrock, U. Raap, B. F. Gibbs, L. Calzolai, V. V. Sumbayev
in Nanoscale (2018)

Variable domain N-linked glycosylation and negative surface charge are key features of monoclonal ACPA: implications for B-cell selection
K. A. Lloyd, J. Steen, K. Amara, P. J. Titcombe, L. Israelsson, S. L. Lundstrom, D. Zhou, R. A. Zubarev, E. Reed, L. Piccoli, C. Gabay, A. Lanzavecchia, D. Baeten, K. Lundberg, D. L. Mueller, L. Klareskog, V. Malmstrom, C. Gronwall
in Eur J Immunol (2018)

CXCL11-dependent induction of FOXP3-negative regulatory T cells suppresses autoimmune encephalomyelitis
Y. Zohar, G. Wildbaum, R. Novak, A. L. Salzman, M. Thelen, R. Alon, Y. Barsheshet, C. L. Karp, N. Karin
in J Clin Invest (2018) vol. 128 pp1200-1201

Chemical stresses fail to mimic the unfolded protein response resulting from luminal load with unfolded polypeptides
T. J. Bergmann, I. Fregno, F. Fumagalli, A. Rinaldi, F. Bertoni, P. J. Boersema, P. Picotti, M. Molinari
in J Biol Chem (2018)

Membrane lipid environment: Potential modulation of chemokine receptor function
M. Thelen, D. F. Legler
in Cytokine (2018)

Conformational Occlusion of Blockade Antibody Epitopes, a Novel Mechanism of GII.4 Human Norovirus Immune Evasion
L. C. Lindesmith, M. L. Mallory, K. Debbink, E. F. Donaldson, P. D. Brewer-Jensen, E. W. Swann, T. P. Sheahan, R. L. Graham, M. Beltramello, D. Corti, A. Lanzavecchia, R. S. Baric
in mSphere (2018) vol. 3

A meiotic XPF-ERCC1-like complex recognizes joint molecule recombination intermediates to promote crossover formation
A. De Muyt, A. Pyatnitskaya, J. Andreani, L. Ranjha, C. Ramus, R. Laureau, A. Fernandez-Vega, D. Holoch, E. Girard, J. Govin, R. Margueron, Y. Coute, P. Cejka, R. Guerois, V. Borde
in Genes Dev (2018) vol. 32 pp283-296

Methods to Study DNA End Resection I: Recombinant Protein Purification
R. Anand, C. Pinto, P. Cejka
in Methods Enzymol (2018) vol. 600 pp25-66

Pillars Article: Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. J. Exp. Med. 1994. 179:1109-1118
F. Sallusto, A. Lanzavecchia
in J Immunol (2018) vol. 200 pp887-896

Dissecting human antibody responses: useful, basic and surprising findings
A. Lanzavecchia
in EMBO Mol Med (2018)

New insights in chemokine signaling
D. F. Legler, M. Thelen
in F1000Res (2018) vol. 7 pp95

Main steps in DNA double-strand break repair: an introduction to homologous recombination and related processes
L. Ranjha, S. M. Howard, P. Cejka
in Chromosoma (2018)

Methods to Study DNA End Resection II: Biochemical Reconstitution Assays
C. Pinto, R. Anand, P. Cejka
in Methods Enzymol (2018) vol. 600 pp67-106

Compartmentalized activities of the pyruvate dehydrogenase complex sustain lipogenesis in prostate cancer
J. Chen, I. Guccini, D. D. Mitri, D. Brina, A. Revandkar, M. Sarti, E. Pasquini, A. Alajati, S. Pinton, M. Losa, G. Civenni, C. V. Catapano, J. Sgrignani, A. Cavalli, R. D'Antuono, J. M. Asara, A. Morandi, P. Chiarugi, S. Crotti, M. Agostini, M. Montopoli, I. Masgras, A. Rasola, R. Garcia-Escudero, N. Delaleu, A. Rinaldi, F. Bertoni, J. Bono, A. Carracedo, A. Alimonti
in Nat Genet (2018)