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Institute for Research in Biomedicine
Istituto di Ricerca in Biomedicina

Via Vincenzo Vela 6 - CH-6500 Bellinzona
Tel. +41 91 820 0300 - Fax +41 91 820 0302 - info [at] irb [dot] usi [dot] ch

Roopesh Anand, PhD

Meccanismi di ricombinazione

Scientist

Via Vela, 6
6500 Bellinzona, Switzerland

Progetti
Promotion of genetic diversity in meiosis: resolution of recombination intermediates
First steps in homologous recombination: DNA end resection
Pubblicazioni
Restoration of Replication Fork Stability in BRCA1- and BRCA2-Deficient Cells by Inactivation of SNF2-Family Fork Remodelers
A. Taglialatela, S. Alvarez, G. Leuzzi, V. Sannino, L. Ranjha, J. W. Huang, C. Madubata, R. Anand, B. Levy, R. Rabadan, P. Cejka, V. Costanzo, A. Ciccia
in Mol Cell (2017) vol. 68 pp414-430 e8
SAMHD1 Promotes DNA End Resection to Facilitate DNA Repair by Homologous Recombination
W. Daddacha, A. E. Koyen, A. J. Bastien, P. E. Head, V. R. Dhere, G. N. Nabeta, E. C. Connolly, E. Werner, M. Z. Madden, M. B. Daly, E. V. Minten, D. R. Whelan, A. J. Schlafstein, H. Zhang, R. Anand, C. Doronio, A. E. Withers, C. Shepard, R. K. Sundaram, X. Deng, W. S. Dynan, Y. Wang, R. S. Bindra, P. Cejka, E. Rothenberg, P. W. Doetsch, B. Kim, D. S. Yu
in Cell Rep (2017) vol. 20 pp1921-1935
The Mre11-Nbs1 Interface Is Essential for Viability and Tumor Suppression
J. H. Kim, M. Grosbart, R. Anand, C. Wyman, P. Cejka, J. H. Petrini
in Cell Rep (2017) vol. 18 pp496-507
Phosphorylated CtIP Functions as a Co-factor of the MRE11-RAD50-NBS1 Endonuclease in DNA End Resection
R. Anand, L. Ranjha, E. Cannavo, P. Cejka
in Mol Cell (2016)
RECQL4 Promotes DNA End Resection in Repair of DNA Double-Strand Breaks
H. Lu, R. A. Shamanna, G. Keijzers, R. Anand, L. J. Rasmussen, P. Cejka, D. L. Croteau, V. A. Bohr
in Cell Rep (2016) vol. 16 pp161-73
The Saccharomyces cerevisiae Mlh1-Mlh3 heterodimer is an endonuclease that preferentially binds to Holliday junctions
L. Ranjha, R. Anand, P. Cejka
in J Biol Chem (2014) vol. 289 pp5674-86