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Institute for Research in Biomedicine
Istituto di Ricerca in Biomedicina

Via Vincenzo Vela 6 - CH-6500 Bellinzona
Tel. +41 91 820 0300 - Fax +41 91 820 0302 - info [at] irb [dot] usi [dot] ch

Lepakshi , PhD

Meccanismi di ricombinazione

Scientist

Via Vela, 6
6500 Bellinzona, Switzerland

Progetti
Promotion of genetic diversity in meiosis: resolution of recombination intermediates
Searching for a homologous partner: DNA strand exchange
Pubblicazioni
Restoration of Replication Fork Stability in BRCA1- and BRCA2-Deficient Cells by Inactivation of SNF2-Family Fork Remodelers
A. Taglialatela, S. Alvarez, G. Leuzzi, V. Sannino, L. Ranjha, J. W. Huang, C. Madubata, R. Anand, B. Levy, R. Rabadan, P. Cejka, V. Costanzo, A. Ciccia
in Mol Cell (2017) vol. 68 pp414-430 e8
Concerted action of the MutLbeta heterodimer and Mer3 helicase regulates the global extent of meiotic gene conversion
Y. Duroc, R. Kumar, L. Ranjha, C. Adam, R. Guerois, K. Md Muntaz, M. C. Marsolier-Kergoat, F. Dingli, R. Laureau, D. Loew, B. Llorente, J. B. Charbonnier, P. Cejka, V. Borde
in Elife (2017) vol. 6
Phosphorylated CtIP Functions as a Co-factor of the MRE11-RAD50-NBS1 Endonuclease in DNA End Resection
R. Anand, L. Ranjha, E. Cannavo, P. Cejka
in Mol Cell (2016)
The MMS22L-TONSL heterodimer directly promotes RAD51-dependent recombination upon replication stress
W. Piwko, L. J. Mlejnkova, K. Mutreja, L. Ranjha, D. Stafa, A. Smirnov, M. M. Brodersen, R. Zellweger, A. Sturzenegger, P. Janscak, M. Lopes, M. Peter, P. Cejka
in EMBO J (2016)
The Saccharomyces cerevisiae Mlh1-Mlh3 heterodimer is an endonuclease that preferentially binds to Holliday junctions
L. Ranjha, R. Anand, P. Cejka
in J Biol Chem (2014) vol. 289 pp5674-86