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Institute for Research in Biomedicine
Istituto di Ricerca in Biomedicina

Via Vincenzo Vela 6 - CH-6500 Bellinzona
Tel. +41 91 820 0300 - Fax +41 91 820 0302 - info [at] irb [dot] usi [dot] ch

Elda Cannavò Cejka, PhD

Meccanismi di ricombinazione

Scientist

Via Vela, 6
6500 Bellinzona, Switzerland

Progetti
First steps in homologous recombination: DNA end resection
Pubblicazioni
Phosphorylated CtIP Functions as a Co-factor of the MRE11-RAD50-NBS1 Endonuclease in DNA End Resection
R. Anand, L. Ranjha, E. Cannavo, P. Cejka
in Mol Cell (2016)
Xrs2 Dependent and Independent Functions of the Mre11-Rad50 Complex
J. Oh, A. Al-Zain, E. Cannavo, P. Cejka, L. S. Symington
in Mol Cell (2016)
Sae2 promotes dsDNA endonuclease activity within Mre11-Rad50-Xrs2 to resect DNA breaks
E. Cannavo, P. Cejka
in Nature (2014) vol. 514 pp122-5
Relationship of DNA degradation by Saccharomyces cerevisiae exonuclease 1 and its stimulation by RPA and Mre11-Rad50-Xrs2 to DNA end resection
E. Cannavo, P. Cejka, S. C. Kowalczykowski
in Proc Natl Acad Sci U S A (2013) vol. 110 ppE1661-8
DNA end resection by Dna2-Sgs1-RPA and its stimulation by Top3-Rmi1 and Mre11-Rad50-Xrs2
P. Cejka, E. Cannavo, P. Polaczek, T. Masuda-Sasa, S. Pokharel, J. L. Campbell, S. C. Kowalczykowski
in Nature (2010) vol. 467 pp112-6
Expression of the MutL homologue hMLH3 in human cells and its role in DNA mismatch repair
E. Cannavo, G. Marra, J. Sabates-Bellver, M. Menigatti, S. M. Lipkin, F. Fischer, P. Cejka, J. Jiricny
in Cancer Res (2005) vol. 65 pp10759-66
Differential killing of mismatch repair-deficient and -proficient cells: towards the therapy of tumors with microsatellite instability
P. Cejka, G. Marra, C. Hemmerle, E. Cannavo, Z. Storchova, J. Jiricny
in Cancer Res (2003) vol. 63 pp8113-7
Methylation-induced G(2)/M arrest requires a full complement of the mismatch repair protein hMLH1
P. Cejka, L. Stojic, N. Mojas, A. M. Russell, K. Heinimann, E. Cannavo, M. di Pietro, G. Marra, J. Jiricny
in EMBO J (2003) vol. 22 pp2245-54