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Institute for Research in Biomedicine
Istituto di Ricerca in Biomedicina

Via Vincenzo Vela 6 - CH-6500 Bellinzona
Tel. +41 91 820 0300 - Fax +41 91 820 0302 - info [at] irb [dot] usi [dot] ch

Mathilde Foglierini Perez, MSc

Regolazione del sistema immunitario

Bioinformatician

Via Vela, 6
6500 Bellinzona, Switzerland

Pubblicazioni
A Human Bi-specific Antibody against Zika Virus with High Therapeutic Potential
J. Wang, M. Bardelli, D. A. Espinosa, M. Pedotti, T. S. Ng, S. Bianchi, L. Simonelli, E. X. Y. Lim, M. Foglierini, F. Zatta, S. Jaconi, M. Beltramello, E. Cameroni, G. Fibriansah, J. Shi, T. Barca, I. Pagani, A. Rubio, V. Broccoli, E. Vicenzi, V. Graham, S. Pullan, S. Dowall, R. Hewson, S. Jurt, O. Zerbe, K. Stettler, A. Lanzavecchia, F. Sallusto, A. Cavalli, E. Harris, S. M. Lok, L. Varani, D. Corti
in Cell (2017) vol. 171 pp229-241 e15
* J. Wang and M. Bardelli contributed equally ; S-M Lok, L.Varani and D. Corti contributed equally.
Public antibodies to malaria antigens generated by two LAIR1 insertion modalities
K. Pieper, J. Tan, L. Piccoli, M. Foglierini, S. Barbieri, Y. Chen, C. Silacci-Fregni, T. Wolf, D. Jarrossay, M. Anderle, A. Abdi, F. M. Ndungu, O. K. Doumbo, B. Traore, T. M. Tran, S. Jongo, I. Zenklusen, P. D. Crompton, C. Daubenberger, P. C. Bull, F. Sallusto, A. Lanzavecchia
in Nature (2017) vol. 548 pp597-601
Do Memory CD4 T Cells Keep Their Cell-Type Programming: Plasticity versus Fate Commitment? T-Cell Heterogeneity, Plasticity, and Selection in Humans
F. Sallusto, A. Cassotta, D. Hoces, M. Foglierini, A. Lanzavecchia
in Cold Spring Harb Perspect Biol (2017)
Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes
N. L. Kallewaard, D. Corti, P. J. Collins, U. Neu, J. M. McAuliffe, E. Benjamin, L. Wachter-Rosati, F. J. Palmer-Hill, A. Q. Yuan, P. A. Walker, M. K. Vorlaender, S. Bianchi, B. Guarino, A. De Marco, F. Vanzetta, G. Agatic, M. Foglierini, D. Pinna, B. Fernandez-Rodriguez, A. Fruehwirth, C. Silacci, R. W. Ogrodowicz, S. R. Martin, F. Sallusto, J. A. Suzich, A. Lanzavecchia, Q. Zhu, S. J. Gamblin, J. J. Skehel
in Cell (2016) vol. 166 pp596-608
Specificity, cross-reactivity and function of antibodies elicited by Zika virus infection
K. Stettler, M. Beltramello, D. A. Espinosa, V. Graham, A. Cassotta, S. Bianchi, F. Vanzetta, A. Minola, S. Jaconi, F. Mele, M. Foglierini, M. Pedotti, L. Simonelli, S. Dowall, B. Atkinson, E. Percivalle, C. P. Simmons, L. Varani, J. Blum, F. Baldanti, E. Cameroni, R. Hewson, E. Harris, A. Lanzavecchia, F. Sallusto, D. Corti
in Science (2016) vol. 353 pp823-6
K. S and M. B contributed equally to this work; D. A. E. ; V. G. ; A. C. ; S. B. and F. V contributed equally to this work; F. S. and D. C contributed equally to this work and are co-corresponding authors.
Platelet-derived growth factor-alpha receptor is the cellular receptor for human cytomegalovirus gHgLgO trimer
A. Kabanova, J. Marcandalli, T. Zhou, S. Bianchi, U. Baxa, Y. Tsybovsky, D. Lilleri, C. Silacci-Fregni, M. Foglierini, B. M. Fernandez-Rodriguez, A. Druz, B. Zhang, R. Geiger, M. Pagani, F. Sallusto, P. D. Kwong, D. Corti, A. Lanzavecchia, L. Perez
in Nat Microbiol (2016) vol. 1 pp16082
Anna Kabanova, Jessica Marcandalli, Tongqing Zhou equally contributed to this work; Antonio Lanzavecchia1and Laurent Perez jointly supervised this work.
Development of broad-spectrum human monoclonal antibodies for rabies post-exposure prophylaxis
P. De Benedictis, A. Minola, E. Rota Nodari, R. Aiello, B. Zecchin, A. Salomoni, M. Foglierini, G. Agatic, F. Vanzetta, R. Lavenir, A. Lepelletier, E. Bentley, R. Weiss, G. Cattoli, I. Capua, F. Sallusto, E. Wright, A. Lanzavecchia, H. Bourhy, D. Corti
in EMBO Mol Med (2016) vol. 8 pp407-21
Paola De Benedictis and Andrea Minola equally contributed to this work.
A LAIR1 insertion generates broadly reactive antibodies against malaria variant antigens
J. Tan, K. Pieper, L. Piccoli, A. Abdi, M. Foglierini, R. Geiger, C. M. Tully, D. Jarrossay, F. M. Ndungu, J. Wambua, P. Bejon, C. S. Fregni, B. Fernandez-Rodriguez, S. Barbieri, S. Bianchi, K. Marsh, V. Thathy, D. Corti, F. Sallusto, P. Bull, A. Lanzavecchia
in Nature (2016) vol. 529 pp105-9
Joshua Tan, Kathrin Pieper, Luca Piccoli equally contributed to this work and Peter Bull and Antonio Lanzavecchia jointly supervised this work.
Somatic mutations and affinity maturation are impaired by excessive numbers of T follicular helper cells and restored by Treg cells or memory T cells
S. Preite, D. Baumjohann, M. Foglierini, C. Basso, F. Ronchi, B. M. Rodriguez, D. Corti, A. Lanzavecchia, F. Sallusto
in Eur J Immunol (2015) vol. 45 pp3010-21
Prophylactic and postexposure efficacy of a potent human monoclonal antibody against MERS coronavirus
D. Corti, J. Zhao, M. Pedotti, L. Simonelli, S. Agnihothram, C. Fett, B. Fernandez-Rodriguez, M. Foglierini, G. Agatic, F. Vanzetta, R. Gopal, C. J. Langrish, N. A. Barrett, F. Sallusto, R. S. Baric, L. Varani, M. Zambon, S. Perlman, A. Lanzavecchia
in Proc Natl Acad Sci U S A (2015) vol. 112 pp10473-8
D.C. and J.Z. contributed equally to this work.
Structures of complexes formed by H5 influenza hemagglutinin with a potent broadly neutralizing human monoclonal antibody
X. Xiong, D. Corti, J. Liu, D. Pinna, M. Foglierini, L. J. Calder, S. R. Martin, Y. P. Lin, P. A. Walker, P. J. Collins, I. Monne, A. L. Suguitan, C. Santos, N. J. Temperton, K. Subbarao, A. Lanzavecchia, S. J. Gamblin, J. J. Skehel
in Proc Natl Acad Sci U S A (2015) vol. 112 pp9430-5
X.X., D.C., and J.L. contributed equally to this work.
T cell immunity. Functional heterogeneity of human memory CD4(+) T cell clones primed by pathogens or vaccines
S. Becattini, D. Latorre, F. Mele, M. Foglierini, C. De Gregorio, A. Cassotta, B. Fernandez, S. Kelderman, T. N. Schumacher, D. Corti, A. Lanzavecchia, F. Sallusto
in Science (2015) vol. 347 pp400-6
Abstract
Reprint
Full Text
Rapid development of broadly influenza neutralizing antibodies through redundant mutations
L. Pappas, M. Foglierini, L. Piccoli, N. L. Kallewaard, F. Turrini, C. Silacci, B. Fernandez-Rodriguez, G. Agatic, I. Giacchetto-Sasselli, G. Pellicciotta, F. Sallusto, Q. Zhu, E. Vicenzi, D. Corti, A. Lanzavecchia
in Nature (2014) vol. 516 pp418-22
Davide Corti and Antonio Lanzavecchia equally contributed to this work.